Recalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horse

  title={Recalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horse},
  author={L. Orlando and Aur{\'e}lien Ginolhac and Guojie Zhang and D. Froese and A. Albrechtsen and M. Stiller and M. Schubert and E. Cappellini and B. Petersen and I. Moltke and Philip L. F. Johnson and M. Fumagalli and Julia T Vilstrup and M. Raghavan and T. Korneliussen and Anna-Sapfo Malaspinas and J. Vogt and Damian Szklarczyk and C. D. Kelstrup and J. Vinther and A. Dolocan and Jesper Stenderup and Amhed Missael Vargas Velazquez and J. Cahill and M. Rasmussen and X. Wang and Jiumeng Min and Grant Zazula and Andaine Seguin-Orlando and Cecilie D Mortensen and K. Magnussen and J. Thompson and Jacobo Weinstock and Kristian Gregersen and K. R{\o}ed and V. Eisenmann and C. Rubin and D. Miller and D. Antczak and M. Bertelsen and S. Brunak and K. Al-Rasheid and O. Ryder and L. Andersson and J. Mundy and A. Krogh and M. Gilbert and K. Kj{\ae}r and T. Sicheritz-Pont{\'e}n and L. Jensen and J. Olsen and M. Hofreiter and R. Nielsen and B. Shapiro and J. Wang and E. Willerslev},
  • L. Orlando, Aurélien Ginolhac, +53 authors E. Willerslev
  • Published 2013
  • Biology, Medicine
  • Nature
  • The rich fossil record of equids has made them a model for evolutionary processes. Here we present a 1.12-times coverage draft genome from a horse bone recovered from permafrost dated to approximately 560–780 thousand years before present (kyr bp). Our data represent the oldest full genome sequence determined so far by almost an order of magnitude. For comparison, we sequenced the genome of a Late Pleistocene horse (43 kyr bp), and modern genomes of five domestic horse breeds (Equus ferus… CONTINUE READING
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