RecBCD- RecFOR-independent pathway of homologous recombination in Escherichia coli.
@article{Buljubai2019RecBCDRP, title={RecBCD- RecFOR-independent pathway of homologous recombination in Escherichia coli.}, author={Maja Buljuba{\vs}i{\'c} and Ana Hlevnjak and J. Repar and Damir Đermi{\'c} and Vedrana Fili{\'c} and I. Weber and K. Zahradka and D. Zahradka}, journal={DNA repair}, year={2019}, pages={ 102670 } }
The RecA protein is a key bacterial recombination enzyme that catalyzes pairing and strand exchange between homologous DNA duplexes. In Escherichia coli, RecA protein assembly on DNA is mediated either by the RecBCD or RecFOR protein complexes. Correspondingly, two recombination pathways, RecBCD and RecF (or RecFOR), are distinguished in E. coli. Inactivation of both pathways in recB(CD) recF(OR) mutants results in severe recombination deficiency. Here we describe a novel, RecBCD- RecFOR… CONTINUE READING
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