RecA-independent mutagenesis in Escherichia coli: effects of umuC and mucB mutations.


We have studied the effects of a umuC mutation on reversion of the lacZ19124 and lacZ19136 frameshift markers of Escherichia coli. Introduction of a umuC::Tn5 mutation into a strain carrying the lacZ19136 marker resulted in enhanced reversion by 9-aminoacridine and the acridine half-mustard ICR191, whereas reversion of the lacZ19124 marker was decreased… (More)


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