Reboxetine modulates the firing pattern of dopamine cells in the ventral tegmental area and selectively increases dopamine availability in the prefrontal cortex.

@article{Linnr2001ReboxetineMT,
  title={Reboxetine modulates the firing pattern of dopamine cells in the ventral tegmental area and selectively increases dopamine availability in the prefrontal cortex.},
  author={Love Linn{\'e}r and H Endersz and Daniel Ohman and Fredrik Bengtsson and Martin Schalling and Torgny H. Svensson},
  journal={The Journal of pharmacology and experimental therapeutics},
  year={2001},
  volume={297 2},
  pages={540-6}
}
Central dopaminergic neurons have been suggested to be involved in the pathophysiology of several psychiatric disorders, including depression, and appear to be modulated by noradrenergic activity both at the nerve terminal level and at the somatodendritic level. In recent years reboxetine, a selective noradrenaline reuptake inhibitor that differs from tricyclic antidepressants by its low affinity for muscarinic, cholinergic and alpha(1)-adrenergic receptors, has been introduced clinically. In… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 52 extracted citations

Noradrenergic Modulation on Dopaminergic Neurons

Neurotoxicity Research • 2018
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 45 references

The control of firing pattern in nigral dopamine neurons: burst firing.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 1984
View 4 Excerpts
Highly Influenced

Dual effects of D-amphetamine on dopamine neurons mediated by dopamine and nondopamine receptors.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2000
View 5 Excerpts
Highly Influenced

Reboxetine: additional benefits to the depressed patient.

Journal of psychopharmacology • 1997
View 4 Excerpts
Highly Influenced

The Rat Brain in Stereotaxic Coordinates

Trends in Neurosciences • 1984
View 2 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…