Rebound of plasma viremia following cessation of antiretroviral therapy despite profoundly low levels of HIV reservoir: implications for eradication.

@article{Chun2010ReboundOP,
  title={Rebound of plasma viremia following cessation of antiretroviral therapy despite profoundly low levels of HIV reservoir: implications for eradication.},
  author={Tae-Wook Chun and J. Shawn Justement and Danielle D Murray and Claire W. Hallahan and Janine Maenza and Ann C Collier and Prameet M. Sheth and Rupert Kaul and Mario Ostrowski and Susan Moir and Colin M. Kovacs and Anthony S. Fauci},
  journal={AIDS},
  year={2010},
  volume={24 18},
  pages={2803-8}
}
OBJECTIVES Sustained suppression of plasma viremia in HIV-infected individuals is attainable with antiretroviral therapy (ART); however, eradication of virus that would allow discontinuation of ART has been hampered by the persistence of HIV reservoirs. It is of great interest to identify individuals who had received ART for prolonged periods of time with extremely low or undetectable HIV reservoirs and monitor plasma viremia following discontinuation of therapy. METHODS We measured the size… CONTINUE READING
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