Rebound insomnia: its determinants and significance.

  title={Rebound insomnia: its determinants and significance.},
  author={Timothy A. Roehrs and G{\"u}nth{\'e}r Vogel and Thomas Roth},
  journal={The American journal of medicine},
  volume={88 3A},
Rebound insomnia is a sleep disturbance that occurs on discontinuation of benzodiazepine hypnotic drugs. It has been reported in both patients and healthy normal subjects and is characterized by increased wakefulness above the person's baseline levels. This article reviews that available information regarding determinants, possible mechanisms, and clinical significance of rebound insomnia. It is concluded that rebound insomnia is a disturbance of one or two nights' duration that primarily… CONTINUE READING