Reassessment of the subcellular localization of p63.

  title={Reassessment of the subcellular localization of p63.},
  author={Anja Schweizer and J. J. Rohrer and Jan W. Slot and Hans J. Geuze and Stuart Kornfeld},
  journal={Journal of cell science},
  volume={108 ( Pt 6)},
p63 is a type II integral membrane protein that has previously been suggested to be a resident protein of a membrane network interposed between the ER and the Golgi apparatus. In the present study, we have produced a polyclonal antibody against the purified human p63 protein to reassess the subcellular distribution of p63 by confocal immunofluorescence, immunoelectron microscopy, and cell fractionation. Double immunofluorescence of COS cells showed significant colocalization of p63 and a KDEL… CONTINUE READING
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