Reassessment of gamma-glutamyl transpeptidase to platelet ratio (GPR): a large-sample, dynamic study based on liver biopsy in a Chinese population with chronic hepatitis B virus (HBV) infection.

Abstract

*Predetermined cut-off values of GPR were used (0.32 to distinguish significant fibrosis, 0.32 to distinguish extensive fibrosis and 0.56 to distinguish cirrhosis). †Predetermined cut-off values of APRI were used (0.5 and 1.5 to distinguish significant fibrosis, and 1.0 and 2.0 to distinguish cirrhosis). ‡Predetermined cut-off values of FIB-4 were used (1.45 and 3.25 to distinguish extensive fibrosis). APRI, aspartate aminotransferase to platelet ratio index; AUROC, area under the receiver operating characteristic curve; FIB-4, fibrosis index based on four factors; GPR, gammaglutamyl transpeptidase to platelet ratio; HBV, hepatitis B virus; LR, likelihood ratio; NPV, negative predictive value; PPV, positive predictive value. Letter

DOI: 10.1136/gutjnl-2017-313896

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Cite this paper

@article{Zhang2017ReassessmentOG, title={Reassessment of gamma-glutamyl transpeptidase to platelet ratio (GPR): a large-sample, dynamic study based on liver biopsy in a Chinese population with chronic hepatitis B virus (HBV) infection.}, author={Wei Zhang and Mimi Sun and Gang Chen and Yong An and Chunlei Lv and Yongqing Wang and Qinghua Shang}, journal={Gut}, year={2017} }