Reassembly of shattered chromosomes in Deinococcus radiodurans

@article{Zahradka2006ReassemblyOS,
  title={Reassembly of shattered chromosomes in Deinococcus radiodurans},
  author={K. Zahradka and D. Slade and A. Bailone and S. Sommer and D. Averbeck and M. Petranovi{\'c} and Ariel B. Lindner and Miroslav Radman},
  journal={Nature},
  year={2006},
  volume={443},
  pages={569-573}
}
  • K. Zahradka, D. Slade, +5 authors Miroslav Radman
  • Published 2006
  • Medicine, Biology
  • Nature
  • Dehydration or desiccation is one of the most frequent and severe challenges to living cells. [...] Key Method In ESDSA, chromosomal fragments with overlapping homologies are used both as primers and as templates for massive synthesis of complementary single strands, as occurs in a single-round multiplex polymerase chain reaction. This synthesis depends on DNA polymerase I and incorporates more nucleotides than does normal replication in intact cells. Newly synthesized complementary single-stranded extensions…Expand Abstract
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