Rear-fanged snake venoms : an untapped source of novel compounds and potential drug leads

@inproceedings{Saviola2014RearfangedSV,
  title={Rear-fanged snake venoms : an untapped source of novel compounds and potential drug leads},
  author={Anthony J. Saviola and E. Peichoto and Stephen P Mackessy},
  year={2014}
}
Animal venoms represent a diverse source of potentially valuable therapeutic compounds due to the high specificity and the potent biological activity of many toxins. Snake venom toxins, particularly disintegrins and proteases from viper venoms, have yielded therapeutics with anti-cancer and hemostatic dysfunction activities. However, venoms from rear-fanged ‘‘colubrid’’ snakes have rarely been analyzed from the perspective of potential lead compound development. Here, we discuss recent progress… CONTINUE READING

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