Reappraising Starling: the physiology of the microcirculation

@article{Jacob2013ReappraisingST,
  title={Reappraising Starling: the physiology of the microcirculation},
  author={M. Jacob and D. Chappell},
  journal={Current Opinion in Critical Care},
  year={2013},
  volume={19},
  pages={282–289}
}
Purpose of reviewVascular permeability is traditionally explained by Starling's principle, describing two opposing forces across the endothelial cell line to maintain compartments in balance. Several contradictions to this principle have recently questioned its validity. Recent findingsHydraulic conductivity is kept low by a properly working endothelial surface layer, created by binding and intercalating plasma constituents with the structural elements of an endothelial glycocalyx. Limiting… Expand
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