Reappraisal of serum insulin-like growth factor-I (IGF-1) measurement in the detection of isolated and combined growth hormone deficiency (GHD) during the transition period.

@article{Boguszewski2013ReappraisalOS,
  title={Reappraisal of serum insulin-like growth factor-I (IGF-1) measurement in the detection of isolated and combined growth hormone deficiency (GHD) during the transition period.},
  author={Cesar L Boguszewski and Claudio Silva de Lacerda and Luiz de Lacerda Filho and J. Carvalho and Margaret C S Boguszewski},
  journal={Arquivos brasileiros de endocrinologia e metabologia},
  year={2013},
  volume={57 9},
  pages={
          709-16
        }
}
OBJECTIVE To evaluate the accuracy of serum IGF-1 in the detection of isolated (IGHD) or combined growth hormone deficiency (CGHD) at the transition phase. SUBJECTS AND METHODS Forty nine patients with GHD during childhood [16 with IGHD (10 men) and 33 with CGHD (24 men); age 23.2 ± 3.5 yrs.] were submitted to an insulin tolerance test (ITT) with a GH peak < 5 µg/L used for the diagnosis of GHD at the transition phase. Pituitary function and IGF-1 measurements were evaluated in the basal… CONTINUE READING

Figures, Tables, and Topics from this paper.

References

Publications referenced by this paper.
SHOWING 1-10 OF 28 REFERENCES

Guidelines for the treatment of growth hormone excess IGF-1 measurement in the transition period Co py rig ht © A BE & M to do s o s d ire ito s r es er va do s

A Giustina, A Barkan, +3 authors E Ghigo
  • Arq Bras Endocrinol Metab
  • 2013
VIEW 9 EXCERPTS
HIGHLY INFLUENTIAL

Growth hormone replacement throughout life: insights into age-related responses to treatment.

  • Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society
  • 2007
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Similar clinical features among patients with severe adult growth hormone deficiency diagnosed with insulin tolerance test or arginine or glucagon stimulation tests.

  • Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
  • 2012
VIEW 1 EXCERPT

Normal values of serum IGF-1 in adults: results from a Brazilian population.

  • Arquivos brasileiros de endocrinologia e metabologia
  • 2010
VIEW 2 EXCERPTS