Corpus ID: 13222758

Reappearance and long-term maintenance of connexin32 in proliferated adult rat hepatocytes: use of serum-free L-15 medium supplemented with EGF and DMSO.

@article{Kojima1995ReappearanceAL,
  title={Reappearance and long-term maintenance of connexin32 in proliferated adult rat hepatocytes: use of serum-free L-15 medium supplemented with EGF and DMSO.},
  author={T. Kojima and T. Mitaka and D. Paul and M. Mori and Y. Mochizuki},
  journal={Journal of cell science},
  year={1995},
  volume={108 ( Pt 4)},
  pages={
          1347-57
        }
}
Intercellular communication, especially gap junctional communication, is thought to be one of the highly differentiated functions of hepatocytes. In primary cultures of rat hepatocytes, it has been considered that the maintenance and the reinduction of differentiated functions is very difficult. In the present study, we succeeded in inducing the gap junctional protein connexin32 (Cx32) in adult rat hepatocytes cultured in serum-free L-15 medium supplemented with epidermal growth factor (EGF… Expand
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