Reanalysis of The National Institute of Mental Health Treatment of Depression Collaborative Research Program General Effectiveness Report

@article{Klein1993ReanalysisOT,
  title={Reanalysis of The National Institute of Mental Health Treatment of Depression Collaborative Research Program General Effectiveness Report},
  author={Donald F. Klein and Donald C. Ross},
  journal={Neuropsychopharmacology},
  year={1993},
  volume={8},
  pages={241-251}
}
The National Institute of Mental Health (NIMH) Treatment of Depression Collaborative Research Program General Effectiveness Report statistical analyses are criticized. Their analyses, which fostered the belief that the active treatments were indistinguishable, were compromised by an inappropriately stringent level of significance with regard to both heterogeneity of slope and pairwise group differences. Once slope heterogeneity is detected, the Johnson-Neyman technique is more appropriate than… CONTINUE READING