Realizing the potential of positron emission tomography with 18F-fluorodeoxyglucose to improve the treatment of Alzheimer's disease.

@article{Foster2008RealizingTP,
  title={Realizing the potential of positron emission tomography with 18F-fluorodeoxyglucose to improve the treatment of Alzheimer's disease.},
  author={Norman L. Foster and Angela Y. Wang and Tolga Tasdizen and P. Thomas Fletcher and J. M. Hoffman and Robert A. Koeppe},
  journal={Alzheimer's & dementia : the journal of the Alzheimer's Association},
  year={2008},
  volume={4 1 Suppl 1},
  pages={S29-36}
}
Positron emission tomography (PET) with 18F-fluorodeoxyglucose (FDG-PET) thus far rarely has been used to advance the development of new treatments for Alzheimer's disease (AD). Now that FDG-PET with standard acquisition protocols for dementia is widely available, change in cerebral glucose metabolism is a feasible outcome variable for clinical drug trials. Individual analysis of FDG-PET results also might prove valuable. FDG-PET can detect metabolic changes very early in the course of AD and… CONTINUE READING

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