Realized immune response is enhanced in long-lived puc and chico mutants but is unaffected by dietary restriction.

@article{Libert2008RealizedIR,
  title={Realized immune response is enhanced in long-lived puc and chico mutants but is unaffected by dietary restriction.},
  author={Sergiy Libert and Yufang Chao and Jessica Zwiener and Scott D. Pletcher},
  journal={Molecular immunology},
  year={2008},
  volume={45 3},
  pages={810-7}
}
The immune system is vital for the immediate survival of multicellular organisms by protecting them from the damaging effects of bacterial infections, viruses, and toxic molecules. It has been hypothesized that the immune system plays a pivotal role in determining longevity. We investigated the efficiency of the innate immune system in Drosophila carrying the longevity extending mutations puc (JNK signaling pathway, stress response) and chico (insulin signaling pathway), as well as animals… CONTINUE READING