Reality distortion is related to the structure of the salience network in schizophrenia.

@article{Palaniyappan2011RealityDI,
  title={Reality distortion is related to the structure of the salience network in schizophrenia.},
  author={Lena Palaniyappan and Pavan Kumar Mallikarjun and Verghese Joseph and Thomas P. White and Peter F. Liddle},
  journal={Psychological medicine},
  year={2011},
  volume={41 8},
  pages={1701-8}
}
BACKGROUND An intrinsic cerebral network comprising the anterior cingulate and anterior insula (the salience network) is considered to play an important role in salience detection in healthy volunteers. Aberrant salience has been proposed as an important mechanism in the production of psychotic symptoms such as delusions and hallucinations (reality distortion). We investigated whether structural deficits in the salience network are associated with the reality distortion seen in schizophrenia… CONTINUE READING