Realgar bioleaching solution suppress ras excessive activation by increasing ROS in Caenorhabditis elegans.

Abstract

Although realgar bioleaching solution (RBS) has been proved to be a potential candidate for cancer therapy, the mechanisms of RBS anticancer are still far from being completely understood. Dosed with RBS in C. elegans, the multivulva phenotype resulting from oncogenic ras gain-of-function was inhibited in a dose dependent manner. It could be abrogated by… (More)
DOI: 10.1007/s12272-013-0182-7

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