Real-time restoration of white-light confocal microscope optical sections

@article{Balasubramanian2007RealtimeRO,
  title={Real-time restoration of white-light confocal microscope optical sections},
  author={Madhusudhanan Balasubramanian and S. Sitharama Iyengar and Roger W. Beuerman and Juan Reynaud and Peter R. Wolenski},
  journal={Journal of electronic imaging},
  year={2007},
  volume={16 3},
  pages={330091-3300911}
}
Confocal microscopes (CM) are routinely used for building 3-D images of microscopic structures. Nonideal imaging conditions in a white-light CM introduce additive noise and blur. The optical section images need to be restored prior to quantitative analysis. We present an adaptive noise filtering technique using Karhunen-Loéve expansion (KLE) by the method of snapshots and a ringing metric to quantify the ringing artifacts introduced in the images restored at various iterations of iterative Lucy… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 24 references

The development and application of a white-light confocal microscope in the morphologic and anatomic characterization of cells within the cornea

  • Kaufman, SC
  • PhD thesis. Louisiana State University School of…
  • 1996
Highly Influential
4 Excerpts

Dutch Society for Pattern Recognition and Image Processing, Drift. Prefiltering: Reducing the noise sensitivity of non-linear image restoration algorithms

  • Van Kempen GMP, LJ VanVliet
  • Fourth Quinquennial Review
  • 2001

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