Real-time prediction of hand trajectory by ensembles of cortical neurons in primates

@article{Wessberg2000RealtimePO,
  title={Real-time prediction of hand trajectory by ensembles of cortical neurons in primates},
  author={Johan Wessberg and Christopher R. Stambaugh and Jerald D. Kralik and Pamela D. Beck and Mark Laubach and John K. Chapin and Jung Kim and S. James Biggs and Mandayam A. Srinivasan and Miguel A. L. Nicolelis},
  journal={Nature},
  year={2000},
  volume={408},
  pages={361-365}
}
Signals derived from the rat motor cortex can be used for controlling one-dimensional movements of a robot arm. It remains unknown, however, whether real-time processing of cortical signals can be employed to reproduce, in a robotic device, the kind of complex arm movements used by primates to reach objects in space. Here we recorded the simultaneous activity of large populations of neurons, distributed in the premotor, primary motor and posterior parietal cortical areas, as non-human primates… 

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