Real-time observation of glomerular hemodynamic changes in diabetic rats: effects of insulin and ARB.

@article{Li2004RealtimeOO,
  title={Real-time observation of glomerular hemodynamic changes in diabetic rats: effects of insulin and ARB.},
  author={Bing Nan Li and Jian Yao and Kazuko Kawamura and Yukiko Oyanagi-Tanaka and Mari Hoshiyama and Tetsuo Morioka and Fumitake Gejyo and Makoto Uchiyama and Takashi Oite},
  journal={Kidney international},
  year={2004},
  volume={66 5},
  pages={1939-48}
}
BACKGROUND The progression of diabetic nephropathy is closely related to disturbances in glomerular hemodynamics, such as glomerular hypertension and/or hyperperfusion. The aim of this study was to observe and to analyze glomerular hemodynamics in rats with diabetes mellitus (DM) in vivo using confocal laser scan microscopy (CLSM). We also examined the effects of candesartan cilexetil (TCV-116), a selective angiotensin II type 1 receptor blocker (ARB), on glomerular hemodynamics in DM… CONTINUE READING

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