Real-time measurements of cAMP production in live Dictyostelium cells.


Cyclic AMP has a crucial role during the entire developmental program of the social amoebae Dictyostelium, acting both as an intracellular second messenger and, when secreted, as a directional cue that is relayed to neighboring cells during chemotaxis. Although significant knowledge about cAMP production in chemotaxing cells has been derived from studies… (More)
DOI: 10.1242/jcs.051987


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