Real time measurement of stimulated dopamine release in the conscious rat using fast cyclic voltammetry: dopamine release is not observed during intracranial self stimulation.

@article{Kruk1998RealTM,
  title={Real time measurement of stimulated dopamine release in the conscious rat using fast cyclic voltammetry: dopamine release is not observed during intracranial self stimulation.},
  author={Zygmunt L. Kruk and Survjit Cheeta and Jaime Mill{\'a} and Robert L. Muscat and Jason E. Williams and Paul Willner},
  journal={Journal of neuroscience methods},
  year={1998},
  volume={79 1},
  pages={9-19}
}
Fast cyclic voltammetry (FCV) was used to measure real time release of electrically stimulated endogenous dopamine in the nucleus accumbens (NAc) of conscious freely moving rats for up to 17 days. The method of electrode construction, implantation, electrical stimulation and recording of changes of extracellular dopamine concentration in the conscious rat are described. Rats trained on a continuous reinforcement schedule to perform intracranial self stimulation (ICSS) were implanted with… CONTINUE READING

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