Real-time intradermal continuous glucose monitoring using a minimally invasive microneedle-based system

  title={Real-time intradermal continuous glucose monitoring using a minimally invasive microneedle-based system},
  author={Federico Ribet and G{\"o}ran Stemme and Niclas Roxhed},
  journal={Biomedical Microdevices},
Continuous glucose monitoring (CGM) has the potential to greatly improve diabetes management. The aim of this work is to show a proof-of-concept CGM device which performs minimally invasive and minimally delayed in-situ glucose sensing in the dermal interstitial fluid, combining the advantages of microneedle-based and commercially available CGM systems. The device is based on the integration of an ultra-miniaturized electrochemical sensing probe in the lumen of a single hollow microneedle… 

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