Real-time in vivo imaging of transgenic bioluminescent blood stages of rodent malaria parasites in mice


This protocol describes a methodology for imaging the sequestration of infected erythrocytes of the rodent malaria parasite Plasmodium berghei in the bodies of live mice or in dissected organs, using a transgenic parasite that expresses luciferase. Real-time imaging of infected erythrocytes is performed by measuring bioluminescence produced by the enzymatic… (More)
DOI: 10.1038/nprot.2006.69


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