Real-time imaging of human cortical activity evoked by painful esophageal stimulation.

@article{Hobson2005RealtimeIO,
  title={Real-time imaging of human cortical activity evoked by painful esophageal stimulation.},
  author={Anthony Robert Hobson and P. L. Furlong and S. F. Worthen and Arjan Hillebrand and Gareth Barnes and Krish D. Singh and Q. Aziz},
  journal={Gastroenterology},
  year={2005},
  volume={128 3},
  pages={610-9}
}
BACKGROUND & AIMS Current models of visceral pain processing derived from metabolic brain imaging techniques fail to differentiate between exogenous (stimulus-dependent) and endogenous (non-stimulus-specific) neural activity. The aim of this study was to determine the spatiotemporal correlates of exogenous neural activity evoked by painful esophageal stimulation. METHODS In 16 healthy subjects (8 men; mean age, 30.2 +/- 2.2 years), we recorded magnetoencephalographic responses to 2 runs of 50… CONTINUE READING

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