Real-time imaging and tuning subcellular structures and membrane transport kinetics of single live cells at nanosecond regime.

Abstract

We developed an electric-field exposure microchannel system with 230-nm thin-layer gold electrodes and interfaced it with a single living cell imaging station and a 10-ns electric-pulse (10 nsEP) generator. This design allows us to image intracellular molecules and structures, membrane transport, and viability of single leukemic cells (HL60) while the cells… (More)
DOI: 10.1021/jp9021739

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