Real-time PCR for chloroquine sensitivity assay and for pfmdr1-pfcrt single nucleotide polymorphisms in Plasmodium falciparum.

Abstract

Plasmodium falciparum drug resistance is a major problem in malaria endemic areas. Molecular markers and in vitro tests have been developed to study and monitor drug resistance. However, none, used alone, can provide sufficient data concerning the level of drug resistance and to issue precise guidelines for drug use policies in endemic areas. We propose… (More)

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@article{Monbrison2003RealtimePF, title={Real-time PCR for chloroquine sensitivity assay and for pfmdr1-pfcrt single nucleotide polymorphisms in Plasmodium falciparum.}, author={Fr{\'e}d{\'e}rique de Monbrison and Delphine Raynaud and Christine Latour-Fondanaiche and Anne Staal and Sebastien Favre and Karine Kaiser and François Peyron and St{\'e}phane Picot}, journal={Journal of microbiological methods}, year={2003}, volume={54 3}, pages={391-401} }