Real-time PCR detection and frequency of 16S rDNA mutations associated with resistance and reduced susceptibility to tetracycline in Helicobacter pylori from England and Wales.

@article{Lawson2005RealtimePD,
  title={Real-time PCR detection and frequency of 16S rDNA mutations associated with resistance and reduced susceptibility to tetracycline in Helicobacter pylori from England and Wales.},
  author={Andrew R J Lawson and Nicola Clare Elviss and Robert Owen},
  journal={The Journal of antimicrobial chemotherapy},
  year={2005},
  volume={56 2},
  pages={
          282-6
        }
}
OBJECTIVES To investigate the occurrence of 16S rDNA mutations associated with resistance or reduced susceptibility to tetracycline in Helicobacter pylori isolated in England and Wales, and to develop a real-time PCR assay to detect these DNA polymorphisms from culture and gastric biopsies. METHODS Tetracycline susceptibility was determined by disc diffusion. The MIC of isolates with reduced susceptibility was determined by Etest and agar dilution methods. The 16S rDNA of these isolates was… CONTINUE READING

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16S rRNA mutationmediated tetracycline resistance inHelicobacter pylori.AntimicrobAgents Chemother

  • MM Gerrits, MR de Zoete, NL Arents
  • 2002
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