Reaggregation of Rat Dissociated Myenteric Plexus in Extracellular Matrix Gels

@article{Schfer2000ReaggregationOR,
  title={Reaggregation of Rat Dissociated Myenteric Plexus in Extracellular Matrix Gels},
  author={Karl-Herbert Sch{\~a}fer and Pedro Mestres},
  journal={Digestive Diseases and Sciences},
  year={2000},
  volume={45},
  pages={1631-1638}
}
The aim of this study was to investigate the growth behavior of freshly dissociated myenteric plexus in a three-dimensional extracellular matrix (ECM) environment with and without stimulation of glial cell line-derived neurotrophic factor (GDNF). Therefore, cell suspensions of the dissected myenteric plexus of newborn rats were cultured in freshly prepared gels of commercially available mixtures of collagen, laminin, and hepatoglycans as a first step towards mimicking the natural environment of… CONTINUE READING