Reagent-Controlled Divergent Synthesis of C-Glycosides.

@article{Han2020ReagentControlledDS,
  title={Reagent-Controlled Divergent Synthesis of C-Glycosides.},
  author={Puren Han and Jianchao Liu and Jinxi Liao and Yuan-Hong Tu and Jian-Song Sun},
  journal={The Journal of organic chemistry},
  year={2020}
}
Leveraging on the exquisitely turning on or switching off the directing effect of the C3-OH located o-diphenylphosphanylbenzoyl (o-DPPB) group in glycals, a reagent-controlled protocol for divergent and regio- and stereo-selective synthesis of C-glycosides has been established. In particularly, the silence of the directing effect of o-DPPB was achieved by the introduction of ZnCl2 additive, which is operationally simple and efficient. The flexibility of the novel protocol was exhibited not only… Expand
1 Citations
Palladium-catalyzed C-glycosylation and annulation of o-alkynylanilines with 1-iodoglycals: convenient access to 3-indolyl-C-glycosides.
An efficient and practical approach for the synthesis of 3-indolyl-C-Δ1,2-glycosides through a palladium-catalyzed annulation/C-glycosylation sequence of o-alkynylanilines with 1-iodoglycals has beenExpand

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