Reactivity of metmyoglobin towards phospholipid hydroperoxides.

Ferrylmyoglobin, the high oxidation state of myoglobin analogous to compound II of peroxidases, promotes the peroxidation of palmitoyl-linoleyl-phosphatidylcholine (PLPC) large unilamellar vesicles. This was associated with oxygen consumption and a slow conversion of ferrylmyoglobin to metmyoglobin. The time course of oxygen consumption was characterized by… CONTINUE READING