Reactivity of ebselen and related selenoorganic compounds with 1,2-dichloroethane radical cations and halogenated peroxyl radicals.

Abstract

The reactivity of ebselen, 2-phenyl-1,2-benzisoselenazol-3(2H)one, and structurally related analogues was studied by pulse radiolysis. The rate constant for the reaction of ebselen with trichloromethylperoxyl radicals was determined to be 2.9 X 10(8) M-1 s-1, while its sulfur analogue, 2-phenyl-1,2-benzisothiazol-3(2H)one, was oxidized at much lower rates… (More)

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@article{Schneich1990ReactivityOE, title={Reactivity of ebselen and related selenoorganic compounds with 1,2-dichloroethane radical cations and halogenated peroxyl radicals.}, author={Christian Schӧneich and Vidya Narayanaswami and Ken Asmus and Helmult Sies}, journal={Archives of biochemistry and biophysics}, year={1990}, volume={282 1}, pages={18-25} }