Reactive oxygen species production is involved in quercetin-induced apoptosis in human hepatoma cells.

@article{Chang2006ReactiveOS,
  title={Reactive oxygen species production is involved in quercetin-induced apoptosis in human hepatoma cells.},
  author={Y F Chang and Chin-Wen Chi and J Wang},
  journal={Nutrition and cancer},
  year={2006},
  volume={55 2},
  pages={201-9}
}
Hepatocellular carcinoma (HCC) is the leading cause of cancer mortality in Asia. The aim of this study was to examine whether reactive oxygen species production is involved in quercetin-induced apoptosis in human HCC cell lines. Quercetin inhibited the growth of hepatoma cells in dose and time dependent manners. Quercetin treatment of hepatoma cells resulted in changes of cell cycle progression. The G0/G1phase was decreased and S phase was increased in HA22T/VGH cells after treatment with… CONTINUE READING