Reactive oxygen species in paraventricular nucleus modulates cardiac sympathetic afferent reflex in rats.

@article{Han2005ReactiveOS,
  title={Reactive oxygen species in paraventricular nucleus modulates cardiac sympathetic afferent reflex in rats.},
  author={Ying Han and Ying Zhang and Han-jun Wang and Xing-ya Gao and Wei Wang and Guo-qing Zhu},
  journal={Brain research},
  year={2005},
  volume={1058 1-2},
  pages={82-90}
}
Our previous studies showed that angiotensin II (Ang II) in the paraventricular nucleus (PVN) potentiated the cardiac sympathetic afferent reflex (CSAR) in rats. This study investigated whether the reactive oxygen species (ROS) in the PVN modulated the CSAR and contributed to the effect of Ang II on the CSAR in rats. Under alpha-chloralose and urethane anesthesia, renal sympathetic nerve activity (RSNA), mean arterial pressure (MAP) and heart rate were recorded in sinoaortic-denervated and… CONTINUE READING