Reactive oxygen species derived from NADPH oxidase system is not essential for liver regeneration after partial hepatectomy.

Abstract

BACKGROUND There is suggestive evidence that reactive oxygen species may play a role in the initiation of liver regeneration via a kupffer cell-mediated mechanism involving TNFa and NF-kappa B. In mammalian cells, a major source of reactive oxygen species derives from the membrane-bound NADPH oxidase system (no protein de novo synthesis is required) and it… (More)

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