Reactive oxygen species depolymerize hyaluronan: involvement of the hydroxyl radical.

Abstract

We have previously demonstrated that reactive oxygen species (ROS) are involved in cartilage degradation. A decrease in the size of hyaluronan (HA), which is the major macromolecule in synovial fluid and is responsible for imparting viscosity to it, is reported in arthritis patients. The purpose of this study is to determine the ROS that depolymerize HA… (More)

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.