Reactive oxygen species are critical in the oleic acid-mediated mitogenic signaling pathway in vascular smooth muscle cells.

Abstract

Obese hypertensive patients with cardiovascular risk factor clustering have increased plasma nonesterified fatty acid levels and are at high risk for atherosclerotic events. Our previous studies demonstrated that oleic acid induces a mitogenic response in rat aortic smooth muscle cells (RASMCs) through protein kinase C (PKC)- and extracellular signal… (More)

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@article{Lu1998ReactiveOS, title={Reactive oxygen species are critical in the oleic acid-mediated mitogenic signaling pathway in vascular smooth muscle cells.}, author={G. Lu and Emily Greene and T Nagai and Bernadette M Egan}, journal={Hypertension}, year={1998}, volume={32 6}, pages={1003-10} }