Reactive oxygen species and acute renal failure.

  title={Reactive oxygen species and acute renal failure.},
  author={Karl A Nath and Suzanne M Norby},
  journal={The American journal of medicine},
  volume={109 8},
Acute renal failure is commonly due to acute tubular necrosis (ATN), the latter representing an acute, usually reversible loss of renal function incurred from ischemic or nephrotoxic insults occurring singly or in combination. Such insults instigate a number of processes-hemodynamic alterations, aberrant vascular responses, sublethal and lethal cell damage, inflammatory responses, and nephron obstruction-that initiate and maintain ATN. Eventually, reparative and regenerative processes… CONTINUE READING
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