Reactive oxygen species: role in the development of cancer and various chronic conditions

@article{Waris2006ReactiveOS,
  title={Reactive oxygen species: role in the development of cancer and various chronic conditions},
  author={Gulam Waris and Haseeb Ahsan},
  journal={Journal of Carcinogenesis},
  year={2006},
  volume={5},
  pages={14 - 14}
}
Oxygen derived species such as superoxide radical, hydrogen peroxide, singlet oxygen and hydroxyl radical are well known to be cytotoxic and have been implicated in the etiology of a wide array of human diseases, including cancer. Various carcinogens may also partly exert their effect by generating reactive oxygen species (ROS) during their metabolism. Oxidative damage to cellular DNA can lead to mutations and may, therefore, play an important role in the initiation and progression of… CONTINUE READING
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