Reactive oxygen species, NADPH oxidases, and hypertension.

Reactive oxygen species (ROS) produced in the neuronal, renal, and vascular systems not only influence cardiovascular physiology but are also strongly implicated in pathological signaling leading to hypertension. Different sources of ROS have been identified, ranging from xanthinexanthine oxidase and mitochondria to NADPH oxidase (Nox) enzymes. Of 7 Nox… CONTINUE READING