Reactive oxygen intermediates as second messengers of a general pathogen response.

@article{Baeuerle1996ReactiveOI,
  title={Reactive oxygen intermediates as second messengers of a general pathogen response.},
  author={Patrick A. Baeuerle and Rudolph A Rupec and Heike L Pahl},
  journal={Pathologie-biologie},
  year={1996},
  volume={44 1},
  pages={29-35}
}
Oxygen and derived ROIs became a threat for all organisms more than two billion years ago. Both prokaryotic and higher eukaryotic cells are able to alter their genetic programme in response to changes in the intracellular levels of reactive oxygen intermediates (ROIs). In bacteria and yeast, this response leads to the new synthesis of proteins that protect the induced cells from the consequences of oxidative damage, such as DNA strand breaks, lipid peroxidation and oxidative damage of proteins… CONTINUE READING

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