Reactive oxygen/nitrogen species and the myocardial cell homeostasis: an ambiguous relationship.

@article{Kuster2010ReactiveOS,
  title={Reactive oxygen/nitrogen species and the myocardial cell homeostasis: an ambiguous relationship.},
  author={Gabriela M. Kuster and St{\'e}phanie P. Haeuselmann and Berit I Rosc-Schl{\"u}ter and Vera Lorenz and Otmar Pfister},
  journal={Antioxidants & redox signaling},
  year={2010},
  volume={13 12},
  pages={1899-910}
}
The totality of functional cardiomyocytes and an intact cardiac progenitor cell pool are key players in the myocardial cell homeostasis. Perturbation of either one may compromise the structural and functional integrity of the heart and lead to heart failure. Reactive oxygen/nitrogen species (ROS/RNS) are important regulators of cardiomyocyte viability; more recently, the interrelation between ROS and progenitor cell behavior and fate has moved into the spotlight. Increasing evidence suggests… CONTINUE READING