Reactive metabolites and antioxidant gene polymorphisms in Type 2 diabetes mellitus☆


Type 2 diabetes mellitus (T2DM), by definition is a heterogeneous, multifactorial, polygenic syndrome which results from insulin receptor dysfunction. It is an outcome of oxidative stress caused by interactions of reactive metabolites (RMs) interactions with lipids, proteins and other mechanisms of human body. Production of RMs mainly superoxide (O2(-)) has… (More)
DOI: 10.1016/j.redox.2013.12.001


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