Reactive astrocytes in neural repair and protection.

  title={Reactive astrocytes in neural repair and protection.},
  author={Michael V Sofroniew},
  journal={The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry},
  volume={11 5},
Reactive astrocytosis occurs prominently in response to all forms of CNS injury or disease. The functions of reactive astrocytes are not well understood, and both harmful and beneficial activities have been attributed to these cells. The basic process of reactive astrocytosis is conserved in vertebrate evolution, suggesting fitness-enhancing benefits, but scar-forming reactive astrocytes are often regarded as uniformly detrimental to clinical outcome, in particular, when implicated as… CONTINUE READING
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