• Medicine
  • Published in Clinical neuropathology 1989

Reactive astrocytes and macrophages in the brain stem of SIDS victims? Eleven age- and sex-matched SIDS and control cases.

@article{Oehmichen1989ReactiveAA,
  title={Reactive astrocytes and macrophages in the brain stem of SIDS victims? Eleven age- and sex-matched SIDS and control cases.},
  author={Manfred Oehmichen and P. G. Linke and Karl Zilles and K. Saternus Saternus},
  journal={Clinical neuropathology},
  year={1989},
  volume={8 6},
  pages={
          276-83
        }
}
The investigation was carried out on 11 sudden infant death (SIDS) cases which were compared with age- and sex-matched controls. Six brain nuclei were selected for evaluation. Using immunohistochemical methods, macrophages were selectively demonstrated by detection of lysozyme; reactive astrocytes, by detection of intracytoplasmic albumin (marker of prior impairment of blood-brain barrier function) or GFAP. No lysozyme-positive cells were demonstrable in the brain stem of any of the examined… CONTINUE READING

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