Reactive Oxygen and Nitrogen Species in Pathogenesis of Vascular Complications of Diabetes

@inproceedings{Son2012ReactiveOA,
  title={Reactive Oxygen and Nitrogen Species in Pathogenesis of Vascular Complications of Diabetes},
  author={Seok Man Son},
  booktitle={Diabetes & metabolism journal},
  year={2012}
}
Macrovascular and microvascular diseases are currently the principal causes of morbidity and mortality in subjects with diabetes. Disorders of the physiological signaling functions of reactive oxygen species (superoxide and hydrogen peroxide) and reactive nitrogen species (nitric oxide and peroxynitrite) are important features of diabetes. In the absence of an appropriate compensation by the endogenous antioxidant defense network, increased oxidative stress leads to the activation of stress… CONTINUE READING

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