Reactive Oxygen Species as Mediators of Organ Dysfunction: Potential Benefits of Resuscitation with Ringer’s Ethyl Pyruvate Solution

@inproceedings{Fink2002ReactiveOS,
  title={Reactive Oxygen Species as Mediators of Organ Dysfunction: Potential Benefits of Resuscitation with Ringer’s Ethyl Pyruvate Solution},
  author={Mitchell P. Fink},
  year={2002}
}
Reactive oxygen species (ROS) are reactive, partially reduced derivatives of molecular oxygen (O2). Important ROS in biological systems include superoxide radical anion (O 2 -• ), hydrogen peroxide (H2O2), hydroxyl radical (OH•), and peroxynitrite (ONOO–). Other related nitrogen-containing moieties, such as nitroso-peroxocar-boxylate (ONOOCO 2 - ) and nitrogen dioxide (NO 2 • ), may also be significant [1, 2]. Most cell types are capable of generating ROS under certain conditions. However, the… CONTINUE READING