Reactive Oxygen Species and Nitric Oxide in Cutaneous Leishmaniasis

@article{Horta2012ReactiveOS,
  title={Reactive Oxygen Species and Nitric Oxide in Cutaneous Leishmaniasis},
  author={M. F. Horta and B{\'a}rbara Pinheiro Mendes and E. H. Roma and F. Noronha and J. P. Mac{\^e}do and L. S. Oliveira and Myrian Morato Duarte and L. Q. Vieira},
  journal={Journal of Parasitology Research},
  year={2012},
  volume={2012}
}
  • M. F. Horta, Bárbara Pinheiro Mendes, +5 authors L. Q. Vieira
  • Published 2012
  • Medicine, Biology
  • Journal of Parasitology Research
  • Cutaneous leishmaniasis affects millions of people around the world. Several species of Leishmania infect mouse strains, and murine models closely reproduce the cutaneous lesions caused by the parasite in humans. Mouse models have enabled studies on the pathogenesis and effector mechanisms of host resistance to infection. Here, we review the role of nitric oxide (NO), reactive oxygen species (ROS), and peroxynitrite (ONOO−) in the control of parasites by macrophages, which are both the host… CONTINUE READING
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