Reactive Oxygen Metabolites (ROMs) as an Index of Oxidative Stress in Obstructive Sleep Apnea Patients

  title={Reactive Oxygen Metabolites (ROMs) as an Index of Oxidative Stress in Obstructive Sleep Apnea Patients},
  author={Konstantinos Christou and Nikolaos Markoulis and Anargyros N. Moulas and Chaido Pastaka and Konstantinos I. Gourgoulianis},
  journal={Sleep and Breathing},
Study Objectives: Obstructive sleep apnea syndrome (OSA) is accompanied by oxygen desaturation and arousal from sleep. Free oxygen radicals are highly reactive molecules which could be produced by the OSA phenomenon of hypoxia/reoxygenation: cyclical alterations of arterial oxygen saturation with oxygen desaturation developing in response to apneas followed by resumption of oxygen saturation during hyperventilation. On the basis of these considerations, it was hypothesized that OSA may be… CONTINUE READING
Highly Cited
This paper has 118 citations. REVIEW CITATIONS


Publications citing this paper.
Showing 1-10 of 64 extracted citations

118 Citations

Citations per Year
Semantic Scholar estimates that this publication has 118 citations based on the available data.

See our FAQ for additional information.


Publications referenced by this paper.
Showing 1-10 of 16 references

A simple test to monitor oxidative stress.

International angiology : a journal of the International Union of Angiology • 1999

The role of reactive oxygen species in atherosclerosis

A. Mugge
Z Kardiol • 1998

Obstructive sleep apnea.

Advances in internal medicine • 1994